The polymerizable rhodium complex [(+)-diopRh(AAEMA)] (AAEMA−: deprotonated form of the ligand 2-(acetoacetoxy)-ethylmethacrylate) was obtained by reaction of (cod)Rh(AAEMA) with (+)-diop at −80 °C. Supported chiral complexes have been obtained by copolymerization of [(+)-diopRh(AAEMA)] with N,N-dimethylacrylamide and N,N′-methylenebisacrylamide or by reaction of [(+)-diopRhCl]2 with an opportunely prepared poly(β-ketoesterate). Catalytic tests carried out with the homogeneous catalyst or with both its heterogeneous analogues proved to be active in the enantioselective hydrogenation of methyl-(Z)-α-N-acetamidocinnamate yielding (S)-phenylalanine methylester with ee’s up to 67%.

Synthesis and catalytic activity of new supported rhodium(I) complexes for the enantioselective hydrogenation of methyl-(Z)-α-N-acetamidocinnamate / Mastrorilli, Piero; Rizzuti, Antonino; Romanazzi, Giuseppe; Suranna, Gian Paolo; Gobetto, Roberto; Nobile, Cosimo Francesco. - In: JOURNAL OF MOLECULAR CATALYSIS. A: CHEMICAL. - ISSN 1381-1169. - STAMPA. - 180:1-2(2002), pp. 177-185. [10.1016/S1381-1169(01)00424-1]

Synthesis and catalytic activity of new supported rhodium(I) complexes for the enantioselective hydrogenation of methyl-(Z)-α-N-acetamidocinnamate

Piero Mastrorilli;Antonino Rizzuti;Giuseppe Romanazzi;Gian Paolo Suranna;Cosimo Francesco Nobile
2002-01-01

Abstract

The polymerizable rhodium complex [(+)-diopRh(AAEMA)] (AAEMA−: deprotonated form of the ligand 2-(acetoacetoxy)-ethylmethacrylate) was obtained by reaction of (cod)Rh(AAEMA) with (+)-diop at −80 °C. Supported chiral complexes have been obtained by copolymerization of [(+)-diopRh(AAEMA)] with N,N-dimethylacrylamide and N,N′-methylenebisacrylamide or by reaction of [(+)-diopRhCl]2 with an opportunely prepared poly(β-ketoesterate). Catalytic tests carried out with the homogeneous catalyst or with both its heterogeneous analogues proved to be active in the enantioselective hydrogenation of methyl-(Z)-α-N-acetamidocinnamate yielding (S)-phenylalanine methylester with ee’s up to 67%.
2002
Synthesis and catalytic activity of new supported rhodium(I) complexes for the enantioselective hydrogenation of methyl-(Z)-α-N-acetamidocinnamate / Mastrorilli, Piero; Rizzuti, Antonino; Romanazzi, Giuseppe; Suranna, Gian Paolo; Gobetto, Roberto; Nobile, Cosimo Francesco. - In: JOURNAL OF MOLECULAR CATALYSIS. A: CHEMICAL. - ISSN 1381-1169. - STAMPA. - 180:1-2(2002), pp. 177-185. [10.1016/S1381-1169(01)00424-1]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11589/664
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