The umbilical cord is a peculiar and complex structure, about 50–60 cm in length and 1–2 cm in diameter, that is essentially composed of three vessels, i.e. the umbilical vein and two umbilical arteries, arranged in coils around the vein surrounded by a great amount of support tissue, the Wharton’s Jelly (WJ) that binds and encases the umbilical vessels. WJ is a mucoid connective tissue (5 % cells, 95 % extracellular matrix) described as a three-dimensional spongy network of interlacing collagen fibers and small woven bundles of glycoprotein microfibrils with an interdispersed soluble phase composed by hydrophylic hyaluronans and proteoglycans. WJ grants the protection of the umbilical vessels against compressive forces due to fetal movements and uterine contractions and is very important to guarantee venous and arterial umbilical blood flows. WJ response to mechanical loading is not well understood; another unsolved problem concerns WJ putative contribution to store and release the energy of the cardiac cycle, therefore in maintaining the anterograde flow in the cord arteries. This article presents a preliminary study on the mechanical behavior of umbilical cord. For that purpose, an optical set up based on intrinsic moire´ will be developed. Slices cut in the transverse directions of the cord will be submitted to equibiaxial tests and specimen deformations will be monitored in real time with moire´ by printing a grating on the cord slice. In this way, it will be possible to gather information on the mechanical anisotropy of the cord

A preliminary investigation on the mechanical behavior of umbilical cord with moiré techniques

BOCCACCIO, Antonio;LAMBERTI, Luciano;PAPPALETTERE, Carmine
2015-01-01

Abstract

The umbilical cord is a peculiar and complex structure, about 50–60 cm in length and 1–2 cm in diameter, that is essentially composed of three vessels, i.e. the umbilical vein and two umbilical arteries, arranged in coils around the vein surrounded by a great amount of support tissue, the Wharton’s Jelly (WJ) that binds and encases the umbilical vessels. WJ is a mucoid connective tissue (5 % cells, 95 % extracellular matrix) described as a three-dimensional spongy network of interlacing collagen fibers and small woven bundles of glycoprotein microfibrils with an interdispersed soluble phase composed by hydrophylic hyaluronans and proteoglycans. WJ grants the protection of the umbilical vessels against compressive forces due to fetal movements and uterine contractions and is very important to guarantee venous and arterial umbilical blood flows. WJ response to mechanical loading is not well understood; another unsolved problem concerns WJ putative contribution to store and release the energy of the cardiac cycle, therefore in maintaining the anterograde flow in the cord arteries. This article presents a preliminary study on the mechanical behavior of umbilical cord. For that purpose, an optical set up based on intrinsic moire´ will be developed. Slices cut in the transverse directions of the cord will be submitted to equibiaxial tests and specimen deformations will be monitored in real time with moire´ by printing a grating on the cord slice. In this way, it will be possible to gather information on the mechanical anisotropy of the cord
2015
SEM Annual Conference and Exposition on Experimental and Applied Mechanics, 2014
978-3-319-06985-2
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11589/16538
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact