Background & Objective: A green one-pot synthesis of oleic acid (1) derivatives is promoted by Rare Earth Metal (REM) triflates and commercial Molybdenum dioxo dichloride (MoCl 2 O 2 ) in the presence hydrogen peroxide as a green oxidant. Results: The protocol permits to govern the oxidation selectivity by simply choosing the proper combination of Mo and Sc catalysts. Conclusion: Methyl oleate epoxide 2a and azelaic acid 6 thus obtained are valuable industrial intermediates for synthesizing bio-compostable plastics, plasticizers of PVC, lubricating oils, cosmetics and pharmaceuticals (bactericides, anti-inflammatories, etc.).
Green procedure for one-pot synthesis of azelaic acid derivatives using metal catalysis / Grazia Laurenza, A., Casiello, M., Anzivino, M., Caputo, D., Catucci, L., Dell'Anna, M.M., Fusco, C., Rizzi, V., Pantone, V., D’Accolti, L., Nacci, A.. - In: RECENT INNOVATIONS IN CHEMICAL ENGINEERING. - ISSN 2405-5204. - STAMPA. - 11:3(2018), pp. 185-191. [10.2174/2405520411666181102162637]
Green procedure for one-pot synthesis of azelaic acid derivatives using metal catalysis
Maria Michela Dell'Anna;
2018
Abstract
Background & Objective: A green one-pot synthesis of oleic acid (1) derivatives is promoted by Rare Earth Metal (REM) triflates and commercial Molybdenum dioxo dichloride (MoCl 2 O 2 ) in the presence hydrogen peroxide as a green oxidant. Results: The protocol permits to govern the oxidation selectivity by simply choosing the proper combination of Mo and Sc catalysts. Conclusion: Methyl oleate epoxide 2a and azelaic acid 6 thus obtained are valuable industrial intermediates for synthesizing bio-compostable plastics, plasticizers of PVC, lubricating oils, cosmetics and pharmaceuticals (bactericides, anti-inflammatories, etc.).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
