We investigate a method for the detection of influenza A virus in order to reduce the risks associated with its toxicity. Our work is based on the analysis of the optical properties of a whispering gallery mode microresonator interacting with a spherical nanoparticle modeling the virion. The microresonator shows a Q-factor quite high, of the order of 6104. Higher is the Q-factor, higher is the perturbation that the light propagating inside the resonator experiences when interacting with a scattering center, i.e. a nanoparticle. Thus, from the transmission spectrum of the resonator-virion system, we are able to derive the size of nanoparticles having a radius in the range 30 - 100 nm, with a small error with respect to the nanoparticle nominal radius
Hybrid optical resonator for nanostructured virus detection and sizing / Ciminelli, C; Campanella, C. M.; Armenise, M. N.. - STAMPA. - (2011). (Intervento presentato al convegno MeMeA 2011 - 2011 IEEE International Symposium on Medical Measurements and Applications tenutosi a Bari, Italy nel May 30-31, 2011) [10.1109/MeMeA.2011.5966768].
Hybrid optical resonator for nanostructured virus detection and sizing
Ciminelli, C;Campanella, C. M.;Armenise, M. N.
2011-01-01
Abstract
We investigate a method for the detection of influenza A virus in order to reduce the risks associated with its toxicity. Our work is based on the analysis of the optical properties of a whispering gallery mode microresonator interacting with a spherical nanoparticle modeling the virion. The microresonator shows a Q-factor quite high, of the order of 6104. Higher is the Q-factor, higher is the perturbation that the light propagating inside the resonator experiences when interacting with a scattering center, i.e. a nanoparticle. Thus, from the transmission spectrum of the resonator-virion system, we are able to derive the size of nanoparticles having a radius in the range 30 - 100 nm, with a small error with respect to the nanoparticle nominal radiusI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.