Leak detection of hydrogen for medical purposes, based on the monitoring of the optical response of a simple Fabry-Perot microcavity, is proposed to investigate either the occurrence of lactose intolerance, or lactose malabsorption condition. Both pathologic conditions result in bacterial overgrowth in the intestine, which causes increased spontaneous emission of H-2 in the human breath. Two sensitivity figures of merit are introduced to inspect changes in the sensor response, and to relate the microcavity response to a pathologic condition, which is strictly related to a different level of exhaled hydrogen. Different sensor configurations using a metal-dielectric microcavity are reported and discussed in order to make the most of the well-known ability of palladium to spontaneously absorb hydrogen.
Fabry-Perot microcavity sensor for H2-breath-test analysis / Vincenti, M. A.; De Sario, M.; Petruzzelli, Vincenzo; D'Orazio, Antonella; Prudenzano, Francesco; De Ceglia, D.; Scalora, M.. - In: JOURNAL OF APPLIED PHYSICS. - ISSN 0021-8979. - 102:7(2007). [10.1063/1.2785023]
Fabry-Perot microcavity sensor for H2-breath-test analysis
PETRUZZELLI, Vincenzo;D'ORAZIO, Antonella;PRUDENZANO, Francesco;
2007-01-01
Abstract
Leak detection of hydrogen for medical purposes, based on the monitoring of the optical response of a simple Fabry-Perot microcavity, is proposed to investigate either the occurrence of lactose intolerance, or lactose malabsorption condition. Both pathologic conditions result in bacterial overgrowth in the intestine, which causes increased spontaneous emission of H-2 in the human breath. Two sensitivity figures of merit are introduced to inspect changes in the sensor response, and to relate the microcavity response to a pathologic condition, which is strictly related to a different level of exhaled hydrogen. Different sensor configurations using a metal-dielectric microcavity are reported and discussed in order to make the most of the well-known ability of palladium to spontaneously absorb hydrogen.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.