Come dansyl with me! A small library of naphthyl gluco derivatives was synthesised from methyl α‐D‐glucopyranoside without protection/deprotection steps. One library member, dansyl C‐glucoside 5, showed an extraordinary anti‐inflammatory activity, protecting 100 % of mice from sepsis at a dose of 25 μg kg−1
Dansyl C‐Glucoside as a Novel Agent Against Endotoxic Shock / La ferla, Barbara; Spinosa, Valerio; D'Orazio, Giuseppe; Palazzo, Marco; Balsari, Andrea; Foppoli, Anastasia A.; Rumio, Cristiano; Nicotra, Francesco. - In: CHEMMEDCHEM. - ISSN 1860-7179. - STAMPA. - 5:10(2010), pp. 1677-1680. [10.1002/cmdc.201000282]
Dansyl C‐Glucoside as a Novel Agent Against Endotoxic Shock
Giuseppe D'Orazio;
2010-01-01
Abstract
Come dansyl with me! A small library of naphthyl gluco derivatives was synthesised from methyl α‐D‐glucopyranoside without protection/deprotection steps. One library member, dansyl C‐glucoside 5, showed an extraordinary anti‐inflammatory activity, protecting 100 % of mice from sepsis at a dose of 25 μg kg−1File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
