The preparation of N-substituted oxazolinylaziridines and their deprotonation to afford the corresponding aziridinyllithiums is described. The chemical and configurational stability of the lithiated species depends on the N-substituent on the aziridine ring. The trapping with carbonyl compounds of (R*,S*) configurated oxazolinylaziridines is an interesting route for the preparation of functionalised α,β-aziridino-γ-lactones. © 2005 Elsevier Ltd. All rights reserved.
Synthesis and lithiation of oxazolinylaziridines: The N-substituent effect / Luisi, R.; Capriati, V.; Florio, S.; Di Cunto, P.; Musio, B.. - In: TETRAHEDRON. - ISSN 0040-4020. - 61:13(2005), pp. 3251-3260. [10.1016/j.tet.2005.01.045]
Synthesis and lithiation of oxazolinylaziridines: The N-substituent effect
Musio B.
2005-01-01
Abstract
The preparation of N-substituted oxazolinylaziridines and their deprotonation to afford the corresponding aziridinyllithiums is described. The chemical and configurational stability of the lithiated species depends on the N-substituent on the aziridine ring. The trapping with carbonyl compounds of (R*,S*) configurated oxazolinylaziridines is an interesting route for the preparation of functionalised α,β-aziridino-γ-lactones. © 2005 Elsevier Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
