The preparation of N-substituted oxazolinylaziridines and their deprotonation to afford the corresponding aziridinyllithiums is described. The chemical and configurational stability of the lithiated species depends on the N-substituent on the aziridine ring. The trapping with carbonyl compounds of (R*,S*) configurated oxazolinylaziridines is an interesting route for the preparation of functionalised α,β-aziridino-γ-lactones. © 2005 Elsevier Ltd. All rights reserved.

Synthesis and lithiation of oxazolinylaziridines: The N-substituent effect / Luisi, R.; Capriati, V.; Florio, S.; Di Cunto, P.; Musio, B.. - In: TETRAHEDRON. - ISSN 0040-4020. - 61:13(2005), pp. 3251-3260. [10.1016/j.tet.2005.01.045]

Synthesis and lithiation of oxazolinylaziridines: The N-substituent effect

Musio B.
2005-01-01

Abstract

The preparation of N-substituted oxazolinylaziridines and their deprotonation to afford the corresponding aziridinyllithiums is described. The chemical and configurational stability of the lithiated species depends on the N-substituent on the aziridine ring. The trapping with carbonyl compounds of (R*,S*) configurated oxazolinylaziridines is an interesting route for the preparation of functionalised α,β-aziridino-γ-lactones. © 2005 Elsevier Ltd. All rights reserved.
2005
Synthesis and lithiation of oxazolinylaziridines: The N-substituent effect / Luisi, R.; Capriati, V.; Florio, S.; Di Cunto, P.; Musio, B.. - In: TETRAHEDRON. - ISSN 0040-4020. - 61:13(2005), pp. 3251-3260. [10.1016/j.tet.2005.01.045]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11589/223781
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