In this review an overview is given on bio-composite coatings, on their applications and the plasma-based processes for their deposition. In particular, we describe the innovative possibility to deposit, via aerosol-assisted atmospheric pressure plasma, drug containing nano-capsules in a one-step process. The application of these peculiar bio-composite materials as cyto-compatible bactericidal drug release coatings have been examined, with different molecules embedded in the same polyethylene-like plasma-deposited matrix: Vancomycin, gentamicin and lysozyme. In conclusion, a hypothesis on the formation mechanisms of the nano-capsules is proposed, which could be very interesting for numerous potential applications.
Aerosol assisted atmopheric pressure PE-CVD of drug containing nano-capsules / Lo Porto, C.; Palumbo, F.; Treglia, A.; Camporeale, G.; Favia, P.. - In: JAPANESE JOURNAL OF APPLIED PHYSICS. PART 2, LETTERS. - ISSN 0021-4922. - 59:SA(2020), p. 0801. [10.7567/1347-4065/ab4e59]
Aerosol assisted atmopheric pressure PE-CVD of drug containing nano-capsules
Lo Porto C.
;Favia P.
2020-01-01
Abstract
In this review an overview is given on bio-composite coatings, on their applications and the plasma-based processes for their deposition. In particular, we describe the innovative possibility to deposit, via aerosol-assisted atmospheric pressure plasma, drug containing nano-capsules in a one-step process. The application of these peculiar bio-composite materials as cyto-compatible bactericidal drug release coatings have been examined, with different molecules embedded in the same polyethylene-like plasma-deposited matrix: Vancomycin, gentamicin and lysozyme. In conclusion, a hypothesis on the formation mechanisms of the nano-capsules is proposed, which could be very interesting for numerous potential applications.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
