Red blood cells (RBCs) are able to deform and flow through the microcirculation thanks to the viscoelastic properties of their membrane. In this study, we present a FSI framework featuring a finite element RBC viscoelastic model coupled with a lattice-Boltzmann method to assess the impact of deformability, internal viscosity, and membrane viscosity on the RBC dynamics in bounded shear flow. We observed that (i) including a viscoelastic membrane influences more the migration timescale than the final equilibrium position along the channel centerline; (ii) the migration timescale is underestimated when the physiological viscosity contrast and the membrane viscosity are neglected.
ON THE IMPORTANCE OF MEMBRANE VISCOELASTICITY FOR THE TRANSPORT OF RED BLOOD CELLS IN SHEAR FLOW / Mantegazza, Alberto; De Marinis, Dario; De Tullio, Marco Donato. - STAMPA. - I:(2024), pp. 74-77. (Intervento presentato al convegno 8th International Conference on Computational & Mathematical Biomedical Engineering (CMBE2024) tenutosi a Arlington, Virginia, Stati Uniti nel 24-26/06/2024).
ON THE IMPORTANCE OF MEMBRANE VISCOELASTICITY FOR THE TRANSPORT OF RED BLOOD CELLS IN SHEAR FLOW
Alberto Mantegazza
;Dario De Marinis;Marco Donato de Tullio
2024-01-01
Abstract
Red blood cells (RBCs) are able to deform and flow through the microcirculation thanks to the viscoelastic properties of their membrane. In this study, we present a FSI framework featuring a finite element RBC viscoelastic model coupled with a lattice-Boltzmann method to assess the impact of deformability, internal viscosity, and membrane viscosity on the RBC dynamics in bounded shear flow. We observed that (i) including a viscoelastic membrane influences more the migration timescale than the final equilibrium position along the channel centerline; (ii) the migration timescale is underestimated when the physiological viscosity contrast and the membrane viscosity are neglected.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.