Recently the hyperpolarized helium ( 3He) gas used as a new contrast agent for lung imaging diagnostic, like functional magnetic resonance imaging (fMRI), is becoming an important technique for diagnosing diseases and abnormalities in the respiratory tract. In the paper a new modular production of Helium-3 ( 3He) gas hyperpolarized using the metastability exchange optical pumping technique (MEOP) is described. By this new modular device we are able to produce at the pressure of 1000 mbar 1 1 of 3He polarized gas, using two modular low-pressure optical pumping cell each of 4 1 surrounded by magnetic field which transfers through non-magnetic peristaltic compressor the 3He gas to the storage cell. A 27% of polarization at a pressure of 1 mbar is obtained in the optical pumping cell in a single run, while a time of about 20 minutes is needed to pump the gas at final pressure of 1000 mbar in the storage cell.
Modular Hyperpolarized Helium-3 Gas Production By Meop Technique For Medical Applications / Losito, Onofrio; Dimiccoli, Vincenzo; Pagliara, Fabio; Prisco, Raffaele. - ELETTRONICO. - (2012), pp. 353-357. (Intervento presentato al convegno 9th IASTED International Conference on Biomedical Engineering, BioMed 2012 tenutosi a Innsbruck; Austria nel February 15-17, 2012) [10.2316/P.2012.764-162].
Modular Hyperpolarized Helium-3 Gas Production By Meop Technique For Medical Applications
Onofrio Losito;
2012-01-01
Abstract
Recently the hyperpolarized helium ( 3He) gas used as a new contrast agent for lung imaging diagnostic, like functional magnetic resonance imaging (fMRI), is becoming an important technique for diagnosing diseases and abnormalities in the respiratory tract. In the paper a new modular production of Helium-3 ( 3He) gas hyperpolarized using the metastability exchange optical pumping technique (MEOP) is described. By this new modular device we are able to produce at the pressure of 1000 mbar 1 1 of 3He polarized gas, using two modular low-pressure optical pumping cell each of 4 1 surrounded by magnetic field which transfers through non-magnetic peristaltic compressor the 3He gas to the storage cell. A 27% of polarization at a pressure of 1 mbar is obtained in the optical pumping cell in a single run, while a time of about 20 minutes is needed to pump the gas at final pressure of 1000 mbar in the storage cell.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
