A multi-analyte biosensing platform for the selective label-free detection of protein biomarkers has been designed through a three-dimensional model based on the finite element method. The sensing element of the platform is a planar plasmonic nanocavity, consisting of a one-dimensional periodic structure (Bragg grating) in gold, with a defect, placed on the buried oxide of a silicon-on-insulator substrate. The footprint of this sensing element, which has a good chemical stability, is only 1.57 μm 2 . The sensor has a detection limit of 128 pg/mm 2 and a surface sensitivity of 1.8 nm/nm.

Design of a label-free multiplexed biosensing platform based on an ultracompact plasmonic resonant cavity / Dell’Olio, Francesco; Conteduca, Donato; De Palo, Maripina; Sasanelli, Nicola; Ciminelli, Caterina. - STAMPA. - 539:(2019), pp. 263-267. [10.1007/978-3-030-04324-7_34]

Design of a label-free multiplexed biosensing platform based on an ultracompact plasmonic resonant cavity

Dell’Olio, Francesco;Conteduca, Donato;Sasanelli, Nicola;Ciminelli, Caterina
2019-01-01

Abstract

A multi-analyte biosensing platform for the selective label-free detection of protein biomarkers has been designed through a three-dimensional model based on the finite element method. The sensing element of the platform is a planar plasmonic nanocavity, consisting of a one-dimensional periodic structure (Bragg grating) in gold, with a defect, placed on the buried oxide of a silicon-on-insulator substrate. The footprint of this sensing element, which has a good chemical stability, is only 1.57 μm 2 . The sensor has a detection limit of 128 pg/mm 2 and a surface sensitivity of 1.8 nm/nm.
2019
Sensors : proceedings of the Fourth National Conference on Sensors, February 21-23, 2018, Catania, Italy
978-3-030-04323-0
Springer
Design of a label-free multiplexed biosensing platform based on an ultracompact plasmonic resonant cavity / Dell’Olio, Francesco; Conteduca, Donato; De Palo, Maripina; Sasanelli, Nicola; Ciminelli, Caterina. - STAMPA. - 539:(2019), pp. 263-267. [10.1007/978-3-030-04324-7_34]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11589/167734
Citazioni
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact