We deduce a fully analytical model to predict the artifacts of the device handles in single molecule force spectroscopy experiments. As we show, neglecting the handle stiffness can lead to crucial overestimation or underestimation of the stability properties and unfolding thresholds of multistable molecules.
The influence of device handles in single-molecule experiments / Bellino, Luca; Florio, G.; Puglisi, G.. - In: SOFT MATTER. - ISSN 1744-683X. - STAMPA. - 15:(2019), pp. 8680-8690. [10.1039/c9sm01376h]
The influence of device handles in single-molecule experiments
Bellino, Luca;G. Florio;G. Puglisi
2019-01-01
Abstract
We deduce a fully analytical model to predict the artifacts of the device handles in single molecule force spectroscopy experiments. As we show, neglecting the handle stiffness can lead to crucial overestimation or underestimation of the stability properties and unfolding thresholds of multistable molecules.File in questo prodotto:
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