Entropic forces in rotaxane-based daisy chains: Toward tunable nanomechanical systems

Mechanically interlocked polymers and molecules exhibit unique topological, physical, and chemical properties, making them highly promising for applications in molecular machines, molecular switches, artificial muscles, nano-actuators, nano-sensors, and biomedical technologies. While significant progress has been made in their synthesis and practical implementation, theoretical studies remain underexplored. In this work, we examine the role of entropic forces in daisy chain structures incorporating rotaxanes, with the ultimate goal of characterizing entropic nano-springs for use in nanomechanics and nanotechnology. Potential applications include artificial cytoskeletons, synthetic cells, and nano-mechanical logic gates.