An oxidative coupling of amines to give imines in ionic liquids (ILs) under metal-free aerobic conditions has been developed. The high efficiency achievable in ILs is mechanistically explained in terms of activation of the starting materials (benzylamine and molecular oxygen) by an initial electron transfer, promoted by the ionic nature of the solvent. Reactivity data of variously p-substituted benzylamines show a general deactivating effect, which would imply a change in the rate-determining step in the reaction mechanism.
|Titolo:||Ionic liquid-assisted metal-free oxidative coupling of amines to imines|
|Data di pubblicazione:||2014|
|Digital Object Identifier (DOI):||10.1002/ejoc.201402530|
|Appare nelle tipologie:||1.1 Articolo in rivista|