A novel nanophotonic platform with a footprint of approximately 1 μm for label-free detection of protein biomarkers is reported in this paper. The platform has been designed by Finite Element Method simulations. The device target application is the early diagnosis of cardiovascular diseases by the fast analysis of a drop of blood. In particular, the biosensor has been designed for the detection (in plasma) of the human β2-microglobulin, which can be used as predictive biomarker of the peripheral arterial disease. The archived resolution, 0.33 μg/mL, is fully compliant with the selected application.
Resonant Nanoplasmonic Platform for Fast and Early Diagnosis of Cardiovascular Diseases / Dell'Olio, Francesco; De Palo, M.; Conteduca, Donato; Ciminelli, Caterina; Armenise, Mario Nicola. - (2016). (Intervento presentato al convegno IEEE 2nd International Forum on Research and Technologies for Society and Industry Leveraging a better tomorrow, RTSI 2016 tenutosi a Bologna, Italy nel September 7-9, 2016) [10.1109/RTSI.2016.7740555].
Resonant Nanoplasmonic Platform for Fast and Early Diagnosis of Cardiovascular Diseases
DELL'OLIO, Francesco;CONTEDUCA, Donato;CIMINELLI, Caterina;ARMENISE, Mario Nicola
2016-01-01
Abstract
A novel nanophotonic platform with a footprint of approximately 1 μm for label-free detection of protein biomarkers is reported in this paper. The platform has been designed by Finite Element Method simulations. The device target application is the early diagnosis of cardiovascular diseases by the fast analysis of a drop of blood. In particular, the biosensor has been designed for the detection (in plasma) of the human β2-microglobulin, which can be used as predictive biomarker of the peripheral arterial disease. The archived resolution, 0.33 μg/mL, is fully compliant with the selected application.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
