Hyperpolarized helium-3 (3He) gas, is a new contrast agent for lung imaging diagnostic in functional Magnetic Resonance Imaging (fMRI) becoming an important technique to diagnose diseases and abnormalities in the respiratory tract. In this paper is described a new modular production method of 3He gas, hyperpolarized using the Metastability Exchange Optical Pumping Technique (MEOP). A standard set of measurements has been collected considering a prototype developed by ITEL Telecomunicazioni srl, able to produce one litre of 3He polarized gas at the pressure of 1000 mbar. A 27% of polarization at a pressure of 1 mbar is obtained in the optical pumping cell in a single run, while a time of about 20 minutes is needed to pump the gas at a final pressure of 1000 mbar in the storage cell.
Measurements in the hyperpolarized helium-3 for medical applications / Losito, Onofrio; Dimiccoli, V.; DI NISIO, Attilio; Spadavecchia, Maurizio; Prudenzano, Francesco. - (2014), pp. 637-641. (Intervento presentato al convegno 20th IMEKO TC4 Symposium on Measurements of Electrical Quantities: Research on Electrical and Electronic Measurement for the Economic Upturn, Together with 18th TC4 International Workshop on ADC and DCA Modeling and Testing, IWADC 2014 tenutosi a University of Sannio, ita nel 2014).
Measurements in the hyperpolarized helium-3 for medical applications
LOSITO, Onofrio;DI NISIO, Attilio;SPADAVECCHIA, MAURIZIO;PRUDENZANO, Francesco
2014-01-01
Abstract
Hyperpolarized helium-3 (3He) gas, is a new contrast agent for lung imaging diagnostic in functional Magnetic Resonance Imaging (fMRI) becoming an important technique to diagnose diseases and abnormalities in the respiratory tract. In this paper is described a new modular production method of 3He gas, hyperpolarized using the Metastability Exchange Optical Pumping Technique (MEOP). A standard set of measurements has been collected considering a prototype developed by ITEL Telecomunicazioni srl, able to produce one litre of 3He polarized gas at the pressure of 1000 mbar. A 27% of polarization at a pressure of 1 mbar is obtained in the optical pumping cell in a single run, while a time of about 20 minutes is needed to pump the gas at a final pressure of 1000 mbar in the storage cell.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
